This paper presents the biogas yield of various de-oiled cake wastes like groundnut de-oiled cake; coconut de-oiled cake, mustard de-oiled cake, and sesame de-oiled cake under anaerobic digester process in a floating dome type gas digester of 0.5 m3 capacity. The working parameters such as concentration of slurry, total solids, pH, temperature, carbon nitrogen ratio and the effectiveness of inoculums for biogas production was investigated in a batch type process for fixed hydro retention time. Hence, the best deoiled waste materials, that can produce the maximum amount of bogus and percentage of methane fraction from each waste material has been found in a mesophilic temperature range (28oC to 40oC). The results show that groundnuts de-oiled and coconuts de-oiled cakes waste yield the maximum volume of biogas generated from the four substrates are 21.28, 25.26, 19.2 and 16.37 liters, respectively. Quantity of methane fraction was an analysis of the biggest yield has also been carried out along with comparing the four types De-oiled cake waste slurry. The results show that the maximum of 67% of methane fraction for coconut de-oiled cake waste followed by 58% methane fraction for ground de-oiled cake, when compared with other two de-oiled cake wastes.