ChemXpress
ISSN (PRINT):2320 –1967

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Progressive Multifocal Leukoencephalopathy Peer Review Articles

Progressive multifocal leukoencephalopathy (PML) is a severe, myelin-damaging disorder of the central nervous system ( CNS) in an immunosuppression environment superimposed by concurrent autoimmune disorders such as multiple sclerosis and AIDS, or concurrent administration of immune modulatory monoclonal antibody drugs such as natalizumab. The causative agent is a polyomavirus known as the John Cunningham (JCV) virus, which affects oligodendrocytes and astrocytes, resulting in focal, extensive, and progressive demyelination throughout the brain. Following extensive medical studies, the pathogenesis of JCV 's latent and active infection has yet to be fully understood. How the JC virus is transmitted is unclear so there are currently no ways to prevent infection. The best way to avoid PML disease, however, is by maintaining a balanced immune system. This involves beginning treatment with HIV until failure of the immune system.

High Impact List of Articles

Relevant Topics in Chemistry

Awards Nomination

Table of Contents

Google Scholar citation report
Citations : 256

ChemXpress received 256 citations as per Google Scholar report

Citation image

Indexed In

  • CASS
  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • CiteFactor
  • Cosmos IF
  • Directory of Research Journal Indexing (DRJI)
  • Secret Search Engine Labs
  • Scholar Article Impact Factor (SAJI))

View More

For Authors

For Librarians

Flyer

Open Access Journals