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Open Access Articles On Pharmacophore

 A pharmacophore is an abstract description of molecular functions that are essential for molecular recognition of a ligand by way of a biological macromolecule. A pharmacophore is a conceptual clarification of molecular capabilities which can be crucial for molecular identity of a ligand with the aid of a organic macromolecule. The IUPAC explains a pharmacophore to be an ensemble of steric and electronic features this is important to make sure the greatest supramolecular interactions with a selected biological target and to trigger (or block) its biological reaction. A pharmacophore model illustrates how structurally multiple ligands can integrate to a common receptor website. Additionally, pharmacophore fashions are used to classify denovo layout or digital screening novel ligands on the way to connect to the same receptor

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