7187379870
Research & Reviews in BioSciences
ISSN 0974-7532
All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Neuropathology
Neuropathology is the study of diseases of the eyes and of the nervous system, which includes the: Brain, Spinal cord, Body's extensive nerve network. Neuropathology plays a key role in characterizing the pathogenesis of neurodegenerative diseases including forms of neurodegeneration with brain iron accumulation (NBIA). Despite important differences, several genetically diverse forms of NBIA nevertheless share common features in addition to iron deposition, such as the presence of neuroaxonal spheroids. Multiple forms of NBIA also demonstrate tau or synuclein pathology, suggesting parallels with both Alzheimer and Parkinson diseases. This chapter summarizes what has been learned from the study of human patient tissues. Gross and microscopic findings are delineated, and similarities and differences between forms of NBIA are presented. Neuropathologic findings often help characterize fundamental features of disease and provide a springboard for more focused hypothesis-driven studies. Lessons learned from neuropathology thus contribute much to the characterization of the molecular mechanisms of disease.Google Scholar citation report
Citations : 627
Research & Reviews in BioSciences received 627 citations as per Google Scholar report
Indexed In
- Google Scholar
- Open J Gate
- China National Knowledge Infrastructure (CNKI)
- Cosmos IF
- Directory of Research Journal Indexing (DRJI)
- Scholarsteer
- Secret Search Engine Labs
- Euro Pub
- ICMJE
View More