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Genotyping Journals

Genotyping is the process of determining differences in the genetic make-up (genotype) of an individual by examining the individual's DNA sequence using biological assays and comparing it to another individual's sequence or a reference sequence. It reveals the alleles an individual has inherited from their parents. Traditionally genotyping is the use of DNA sequences to define biological populations by use of molecular tools. It does not usually involve defining the genes of an individual. The usefulness of the variants in clinical practice depends on improving the diagnostic prediction or fostering changes in prevention or treatment strategies. There is a compelling need for detailed and extensive studies to establish the cost and effectiveness of genotyping. Although there are still unanswered questions, PG researchers have generated and improved specific tools for novel treatment and handling of cancer patients. With new PG markers being identified and validated, physicians will have ways and means to tailor specific drugs to individual genetic profiles. Over the next few years, the emergence of molecular resistance to new therapies as a result of genomic alterations in cancer will drive diagnostics companies to develop new tests for individualized therapy. The future implementation of the methods for genotyping will lead to personalized treatment and eventually will shift the balance from disease relapse toward disease eradication. Therefore, it is essential that pharmaceutical and biotechnology companies join the efforts to develop accurate and cheap tests for routine diagnostics in pharmacogenomics.

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Google Scholar citation report
Citations : 748

Acta Chimica and Pharmaceutica Indica received 748 citations as per Google Scholar report

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