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Articles On Gestational Diabetes

 Gestational diabetes mellitus (GDM) is increasing in prevalence in tandem with the dramatic increase in the prevalence of overweight and obesity in women of childbearing age. Much controversy surrounds the diagnosis and management of gestational diabetes, emphasizing the importance and relevance of clarity and consensus. If newly proposed criteria are adopted universally a significantly growing number of women will be diagnosed as having GDM, implying new therapeutic challenges to avoid foetal and maternal complications related to the hyperglycemia of gestational diabetes. This review provides an overview of clinical issues related to GDM, including the challenges of screening and diagnosis, the pathophysiology behind GDM, the treatment and prevention of GDM and the long and short term consequences of gestational diabetes for both mother and offspring.American Diabetes Association (ADA) formally classifies GDM as “diabetes first diagnosed in the second or third trimester of pregnancy that is not clearly either preexisting type 1 or type 2 diabetes” . However, the exact threshold for a diagnosis of GDM depends on the criteria used, and so far, there has been a lack of consensus amongst health professionals. Electronic research-literature databases searched included PubMed, Web of Science, Scopus, and Cochrane databases. In order to detect any missed articles during the literature search, reference lists of candidate articles were reviewed for further studies not yet identified. For each excluded study, we determined which elements of the electronic search were not addressed.  

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Relevant Topics in Biochemistry