A variety of different therapeutic process is used for atopic dermatitis. The combination of topical and systemic agents for the treatment of atopic dermatitis has been improved in past decades. Numerous therapies for atopic dermatitis require improved RCTs and comparative trials like corticosteroids vs. calcinerium inhibitors. Dermatitis is an umbrella term for a range of inflammatory skin conditions of varying aetiology. Common manifestations include erythema, scaling, vesicles, itching, and lichenification where there is chronic inflammation. Each type of dermatitis has distinct signs and symptoms, although in practice it may be difficult to differentiate between them and also between other inflammatory skin conditions. Atopic dermatitis is a common, often long-lasting skin disease that affects a large percentage of the world's population. Atopy is a special type of hypersensitivity that is associated with asthma, inhalant allergies (hay fever), and a chronic dermatitis.