+44 7362 049930
Original Article
, Volume: 7( 3)Synthesis and Evaluation of Antifungal Activity of Novel Indole Derivatives
Abstract
Novel Mannich bases of indole were synthesized by using a series of secondary amines and formaldehyde in presence of ethanol with magnetic stirring for 4-6 hours in cold condition. The structures of these compounds were established on the basis of spectral data. The final compounds were screened for antifungal activity against Candida albicans using cup- plate method. Ketoconazole was used as standard drug.
