Visible Spectrophotometric Determination of Amlodipine in Pharmaceutical Formulation and Bulk Drug by using Bromocresol Purple

Author(s): Asgar Ali, Khaja Pasha, S. A. Raju and Syeda Humaira

A simple and sensitive visible spectrophotometric method has been developed for the quantitative estimation of amlodipine in bulk drug and pharmaceutical dosage forms (tablets). Amlodipine exhibited absorption maximum at 410 nm in bromocresol purple 0.05%. 2.4 buffer solution and obeyed Beer’s law in concentration range 4-20 μg/mL. The result of analysis in this method has been validated statistically and by recovery studies. This method is extended for the analysis of drug and in pharmaceutical formulation.

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