Abstract

Synthesis of Some (S)-Alanine Derivatives

Author(s): Radia Mahboub

In this work, an efficient synthesis for the preparation of N-phthaloyl-(S)-alanine (3) and N- phthaloyl-(S)-alanyl chloride (4) has been presented using economical experimental conditions and the N-Phthaloyl-(S)-alanine (3) has been prepared in excellent enantiomeric excess and with quantitative yield. The acyl chlorination has also been modifide and the reaction time has been reduced by adding an excess of DMF. The compound (4) has been obtained in good optically form.


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