All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Synthesis of 6-Chloroflavone from 4-Chlorophenol and their Biocidal Activity

Author(s): Vaishali B Adhau

Flavones are the organic compounds essential for human body found naturally in cereals and herbs. Usually, flavones have been prepared by Baker-Venkatraman rearrangement, which involves the conversion of 2-hydroxyacetophenones into benzoyl esters followed by rearrangement in base to give 1, 3- diketone as a reaction intermediate, which upon cyclization under acidic conditions to afford respective flavones. The present work deals with the synthesis of 6-chloroflavone from 4-chlorophenol and it characterization on the basis of UV-Vis, IR and 1H-NMR spectral data. Also the biocidal activity of synthesized compound have been evaluated against the growth of microorganisms using paper disc method and compared with streptomycin as a standard.

Share this       

Recommended Conferences