Abstract

Synthesis of 3-Halo Flvones from 2-Hydroxy-3-5-Disubstituted Acetophenone

Author(s): R. E. Bhadange, S. V. Kolhe and R. P. Ganorkar

Substituted acetophenone was reacted with substituted benzoic acid in pyridine medium as base in presence of phosphoryl chloride for five hours and the thick mass was decomposed by 1 : 1 HCl to get substituted benzoyloxy substituted acetophenone. This product was further subjected to BVT reaction to get substituted dibenzoyl methane. Substituted dibenzoyl methane is treated with iodine monochlorides in DMF medium gives 3-halo flavones.


Share this