Synthesis and in vitro Antimicrobial Activity of 3-Hepta-O-benzoyl-D- maltosylimino-4-aryl-5-phenylimino-1, 2, 4-dithiazolidines (Hydrochloride)

Author(s): Mamta T. Sangole and Shirish P. Deshmukh

A series of 3-hepta-O-benzoyl-*-D-maltosylimino-4-aryl-5-phenylimino-1, 2, 4-dithiazolidines (hydrochloride) have been synthesized by the interaction of various 1-hepta-O-benzoyl--D-maltosyl-3- aryl thiocarbamides with N-phenyl-S-chloroisothiocarbamoyl chloride. All the compounds investigated for their antimicrobial activities against Proteus vulgaries, Escherichia coli, Salmonella typhimurium, Staphylococcus aureus, Pseudomonas aeruginosar, Riazoctomia and Aspergilus niger. The newly synthesized compounds have been characterized by analytical and IR, 1H NMR and Mass spectral studies. The purity of these was confirmed by TLC.

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