Parası kalmadığı için otobüse binemiyordur ailesi porno izle ona daha yeni para gönderdiği için tekrar porno istemeye utanınca mecburen otostop çekmek için youporn çantasını alarak yol kenarına gelir etekli porno liseli türk kız yol kenarında dururken yanına yaklaşan porno kibar bir gencin onu gideceği yere kadar bırakmak porno izle istemesine çok mutlu olur arabaya bindiklerinde gideceği yer ile porno arabayı kullanan adamın gittiği yer arasında çok mesafe sex izle farkı olduğunu anlayan türk kız bu yaptığı porno indir iyilik karşısında arabada ona memelerini açar porno sapıklaşan adam yol kenarındaki hotelde durarak porno izle üniversiteli otostop çeken türk kızına odada sakso çektirip sikerSynthesis and Antibacterial Activity of Phenothiazine-3-Sulfonate Derivatives| Abstract

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Abstract

Synthesis and Antibacterial Activity of Phenothiazine-3-Sulfonate Derivatives

Author(s): M. Vasudha, G. Mohan Rao, A. Anna Reddy and Vijay Kumar Baru

Phenothiazine derivatives are biologically active and pa vital role in medicinal chemistry. The present report explains a simple and efficient synthesis of title compounds. The compounds are also screened for their biological activity and shown good results. Potassium 1-amino-10,10a-dihydro-4aH-phenothiazine- 3-sulfonate (1) reacts with Benzaldehyde to form Potassium-1-(benzylideneamino)-10,10a-dihydro-4aHphenothiazine- 3-sulfonate (2), which undergoes N-alkylation to give potassium-1-(benzylideneamino)- 10,10a-dihydro-10-((oxiran-2-yl)methyl)-4aH-phenothiazine-3-sulfonate (3). Compound 3 reacts with different amines to give Potassium-1-(benzylideneamino)-10, 10a-dihydro-10-(2-hydroxy-2-(pyrrolidin-1- yl)ethyl)-4aH-phenothiazine-3-sulfonate (4a-e). All the newly synthesized quinoxaline-benzohydrazide derivatives have been characterized by 1H NMR, IR and mass spectroscopic analysis. The synthesized compounds have been screened for antibacterial activity. Most of the compounds show significant antibacterial activity.


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