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Phytochemical Screening and Antifungal Activity of Phyllanthus maderapatensis Linn. Against Selected Human Fungal Pathogens

Author(s): Padma Priya B, Muhammad Ilyas, Hiranmai Yadav R and Thenmozhi M

Phyllanthus maderapatensis belonging to the family euphorbiaceae was screened to evaluate in vitro antifungal activity against selected human pathogenic fungi like Trichophyton rubrum, Aspergillus niger, Candida albicans and Penicillium chrysogenum. The antifungal index of the ethanolic and n-hexane extracts with various concentration of selected plants were determined by agar diffusion method against test human fungal pathogens. With the increase in concentration of various extracts, antifungal activity also increased. An attempt has been made to compare the spectrum of inhibition of Phyllanthus species to that of standard antifungal drugs. Phytochemical analysis of Phyllanthus maderapatensis shows the presence of alkaloids, flavanoids, steroids, carbohydrates etc.

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