Abstract
Pharmaceutical Intermediates in Microbial Chemistry: Linking Microbial Metabolism to Drug Development
Author(s): Irene K. VolkovAbstract Pharmaceutical intermediates are chemically defined compounds formed during the multistep synthesis of active pharmaceutical ingredients. In microbial chemistry, these intermediates play a crucial role as both products of microbial metabolism and substrates for further chemical or biological transformation. Microorganisms offer unique catalytic capabilities that enable the selective and sustainable production of complex intermediates. This article explores the role of pharmaceutical intermediates in microbial chemistry, emphasizing their importance in pathway elucidation, process optimization, and the integration of microbial systems into modern drug development.