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Abstract

New Spectrophotometric Method for Estimation of Lamivudine in Bulk and Pharmaceutical Dosage Forms

Author(s): N. V. Pimpodkar, N. S. Mahajan, R. L. Jadhav, R. S. Nalawade and B. S. Kuchekar

A simple sensitive, rapid, accurate and precise spectrophotometric method has been developed for estimation of lamivudine in bulk and pharmaceutical dosage forms. Lamivudine shows maximum absorbance (max) at 274 nm with molar abosrptivity of 1.117 x 103 lit. mol-1cm.-1 Beer’s law was obeyed in the concentration range of 2.5 to 25 μg/mL. The results obtained with the proposed method are in good agreement with labeled amount, when marketed pharmaceutical preparations were analyzed. Results obtained were validated statistically and by recovery studies and found to be reproducible.


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International Journal of Chemical Sciences received 4270 citations as per google scholar report

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  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research

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