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Abstract

Mutual solubilities of ethylene glycol and organic diluents investigated using gas chromatography and NMR

Author(s): Irina S. Joseph*

The solubility of Ethylene Glycol (EG) in various organic diluents is of utmost importance in a wide range of industrial applications, spanning from chemical synthesis to pharmaceutical formulations. To better understand these solubility behaviors, two powerful analytical techniques, Gas Chromatography (GC), and Nuclear Magnetic Resonance (NMR), are commonly utilized. This review article aims to present a comprehensive overview of recent advancements in the field, particularly in the mutual solubilities of ethylene glycol with organic diluents, with a specific focus on the insights obtained through GC and NMR methodologies. The article delves into an in-depth examination of experimental techniques employed to study the solubility behavior of these systems. It explores the nuances of using GC and NMR in this context, highlighting their significance in providing valuable data and aiding researchers in drawing meaningful conclusions. Furthermore, the review article also discusses thermodynamic modeling approaches used to understand the underlying principles governing the solubility interactions between ethylene glycol and organic diluents. By analyzing these models, researchers can gain a deeper understanding of the factors influencing solubility, leading to a more comprehensive comprehension of the overall system behavior. The practical implications of these findings are explored across diverse industrial sectors, emphasizing the impact of mutual solubilities on various processes. Whether it be in chemical manufacturing or pharmaceutical industries, a profound understanding of the mutual solubility behavior is crucial in optimizing processes, designing efficient formulations, and enhancing product quality. Conclusion, this review article aims to synthesize recent research on the mutual solubilities of ethylene glycol with organic diluents, highlighting the significance of GC and NMR techniques. Through a combination of experimental studies, thermodynamic modeling, and industrial applications, the article provides valuable insights that contribute to advancements in multiple sectors and pave the way for further research in this field.


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