All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


Extractive Spectrophotometric Methods for Estimation of Citalopram Hydrobromide in Bulk and Pharmaceutical Formulation

Author(s): M. Sundarapandian, S. Venkataraman, M. Boopathi, V. Manoj Kumar and M. S. Prakash

Two simple economical, accurate and reproducible visible spectrophotometric methods (A and B) have been developed for the estimation of citalopram hydrobromide in bulk and tablet formulations.The developed methods are based on the formation of colored chloroform extractable ion-pair complexes of drug with bromocresol green (BCG) and bromophenol blue (BPB) in acidic medium.These chloroform extractable ion-pair complexes showed the absorption maxima at 415 nm. Beer’s law plot is linear over the concentration range of 5-20 μg/mL for both methods. The different experimental parameters affecting the development and stability were studied carefully and optimized. Results of analysis for both the methods were validated statistically and by recovery studies.

Share this       
Google scholar citation report
Citations : 4270

International Journal of Chemical Sciences received 4270 citations as per google scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research

Read More