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Development and Validation of RP-HPLC Method for the Estimation of Antiretroviral Drugs in Tablet Dosage Forms

Author(s): K. Parameshwar Rao

Reversed phase liquid chromatographic method has been developed and subsequently validated for the determination of drugs in tablet formulations. Standard stock solutions of different drugs were prepared by transferring accurately weighed drug and dissolving in a solution suitably. This solution was sonicated for 20 min to achieve complete dissolution and made up to the mark with mobile phase. From the standard stock solution different concentrations of working standard solutions of drugs were prepared with the same mobile phase. The developed method offers several advantages in terms of simplicity in mobile phase, mode of elution, easy sample preparation steps and comparative short run time which makes the method specific and reliable for its intended use in routine analysis determination of drug in tablet dosage forms.

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Citations : 4955

International Journal of Chemical Sciences received 4955 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research

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