Parası kalmadığı için otobüse binemiyordur ailesi porno izle ona daha yeni para gönderdiği için tekrar porno istemeye utanınca mecburen otostop çekmek için youporn çantasını alarak yol kenarına gelir etekli porno liseli türk kız yol kenarında dururken yanına yaklaşan porno kibar bir gencin onu gideceği yere kadar bırakmak porno izle istemesine çok mutlu olur arabaya bindiklerinde gideceği yer ile porno arabayı kullanan adamın gittiği yer arasında çok mesafe sex izle farkı olduğunu anlayan türk kız bu yaptığı porno indir iyilik karşısında arabada ona memelerini açar porno sapıklaşan adam yol kenarındaki hotelde durarak porno izle üniversiteli otostop çeken türk kızına odada sakso çektirip sikerDesign Synthesis and Preliminary Antibacterial Evaluation of Schiff Base Metal Complexes of Ampicillin and Cephalexin| Abstract

Abstract

Design Synthesis and Preliminary Antibacterial Evaluation of Schiff Base Metal Complexes of Ampicillin and Cephalexin

Author(s): Abbas H Abdulsada, Noor H Nasser and Ahmed K Hussein

In the present study, new Schiff bases derived from two beta lactam antibiotics, ampicillin and cephalexin were synthesized from condensation of the aforementioned drugs with Terephthalaldehyde and their metal complexes counterparts with copper (II) have been synthesized. In both drugs the free amino group of the acylamino side chain allowed to react with Terephthalaldehyde to obtain Schiff bases which were, subsequently, allowed to react with copper chloride separately to form Schiff base copper complexes. All the derivatives and metal complexes are analyzed by FT-IR, elemental analysis and 1H NMR analysis. The antibacterial activity of the prepared compounds was screened against several bacterial strains namely S. aureus, E. coli and P. aeruginosa. The antibacterial screening tests elicit that both copper complexes besides Schiff bases exhibited promising antibacterial activity against these microorganisms so that they are of improved antibacterial activity than the parent drugs.


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Citations : 748

Acta Chimica and Pharmaceutica Indica received 748 citations as per Google Scholar report

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