Design, Synthesis and In Vitro Antimicrobial Activity of Trisubstituted S-Triazine

Author(s): Anil Rathavi and M. K. Thakor

A variety of N-[4-chloro-6-(quinolin-8-yloxy)-1,3,5-triazin-2-yl]-2-methylquinolin-8-amine, G were synthesized by using 2-methylquinolin-8-amine, quinolin-8-ol and cyanuric chloride. Structures of these compounds were confirmed by IR and 1H NMR spectral analysis. The newly synthesized compounds were also evaluated for antimicrobial activity against variety of bacterial strains and some of these compounds have shown significant antibacterial and antifungal activities.

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