Parası kalmadığı için otobüse binemiyordur ailesi porno izle ona daha yeni para gönderdiği için tekrar porno istemeye utanınca mecburen otostop çekmek için youporn çantasını alarak yol kenarına gelir etekli porno liseli türk kız yol kenarında dururken yanına yaklaşan porno kibar bir gencin onu gideceği yere kadar bırakmak porno izle istemesine çok mutlu olur arabaya bindiklerinde gideceği yer ile porno arabayı kullanan adamın gittiği yer arasında çok mesafe sex izle farkı olduğunu anlayan türk kız bu yaptığı porno indir iyilik karşısında arabada ona memelerini açar porno sapıklaşan adam yol kenarındaki hotelde durarak porno izle üniversiteli otostop çeken türk kızına odada sakso çektirip sikerCirculation and molecular epidemiology of enteroviruses in paralyzed, immunodeficient and healthy individuals in Tunisia, a country with polio free status since decades| Abstract

Abstract

Circulation and molecular epidemiology of enteroviruses in paralyzed, immunodeficient and healthy individuals in Tunisia, a country with polio free status since decades

Author(s): Anissa Chouikha

This report is an overview of Enterovirus (EV) detection in Tunisian polio-suspected paralytic cases (Acute Flaccid Paralysis (AFP) cases), healthy contacts, and patients with Primary Immunodeficiencies (PID), during 11 years. A total of 2735 clinical samples were analyzed for EV isolation and type identification according to World Health Organization recommended protocols. The three Poliovirus (PV) serotypes and 28 different Non-polio Enteroviruse (NPEV) were detected. The NPEV detection rate was4,3%, 2.8%, and 12.4% in AFP cases, healthy contacts, and PID patients, respectively. The predominant species was EV-B and circulation of viruses from species EV-A was noted since 2011. All PVs detected were of Sabin origin. The PV detection rate was higher in PID patients as compared to AFP cases and contacts (6.8%, 1.5%and 1.3% respectively). PV2was not detected since 2015. Using nucleotide sequencing of the entire VP1 region, 61 strains were characterized as Sabin-like. Among them, six strains of types 1 and 3 PV were identified as pre-VDPV. Five types 2 PV, four strains belonging to type 1 PV, and two strains belonging to type 3 PV were classified as iVDPVs. The data presented provide a comprehensive picture of EVs circulating in Tunisia over the 11-years, reveal changes in their epidemiology as compared to previous studies, and highlight the need to set up a warning system to avoid unnoticed PVs.


Share this