Abstract
API Intermediates in Microbial Chemistry: Microbial Pathways Supporting Active Pharmaceutical Ingredient
Author(s): Pavel S. NovakAbstract API intermediates are key chemical compounds formed during the synthesis of active pharmaceutical ingredients. In microbial chemistry, these intermediates are increasingly generated or modified through microbial metabolic and enzymatic processes. Microorganisms provide highly selective and sustainable routes for producing structurally complex intermediates that are difficult to obtain through conventional chemical synthesis. This article examines the role of API intermediates in microbial chemistry, highlighting their importance in metabolic pathway analysis, biocatalytic efficiency, and the development of environmentally responsible pharmaceutical manufacturing strategies.