Abstract

Anticancer and Antioxidant Activities of 2-Aminobenzoic Acid (2-Oxo-1, 2 -dihydro-indol-3-ylidene) Hydrazides

Author(s): G. Sammaiah, N. Narsaiah, J. Krishnaveni, G. Dayakar and M. Sarangapani

In this communication, the anticancer and antioxidant activities of some new 2-aminobenzoic acid (2-oxo-1, 2-dihydro-indol-3-ylidene) hydrazides are presented. The new compounds were prepared by the condensation of indole-2, 3-diones with 2-aminobenzoic acid hydrazide. All the compounds were evaluated for anticancer activity (against HeLa cell lines, IMR-32 cell lines) and antioxidant activity. Some of the compounds exhibited moderate anticancer activity against the cell lines employed and promising antioxidant activity.