Antibacterial and Antifungal Activities of Some Novel N-Lactosides

Author(s): P. T. Agrawal, Y. A. Alia and S. P. Deshmukh

A series of N-lactosides like 1-hepta-O-benzoyl--D-lactosyl-3-aryl thiocarbamides, thiocarbamates and benzothiazolyl thiocarbamides were synthesized by the interaction of 1-hepta-Obenzoyl- -D-lactosyl isothiocyanate with aryl amines, alcohols and 2-amino benzothiazole / substituted benzothiazoles, respectively. 1-Aryl-5-hepta-O-benzoyl--D-lactosyl-2-S-benzyl-2, 4-isoditiobiurets were synthesized by the interaction of 1-hepta-O-benzoyl--D-lactosyl isothiocyanate with S-benzyl-aryl isothiocarbamides. 3 – Hepta – O - benzoyl – 6 - D - lactosylimino - 5- arylimino - 1, 2, 4 - dithiazolidines (hydrobromide) were synthesized by oxidative debenzylation and cyclization of 1-aryl-5- hepta-O-benzoyl--D-lactosyl-2-S-benzyl-2, 4-isodithiobiurets with molecular bromine in chloroform medium. These newly synthesized compounds were characterized on the basis of usual chemical transformations, IR, NMR and mass spectral analysis. In the present investigation, activities of these Nlactosides against pathogenic baceteria and fungi such as E. Coli, S. aureus, P. vulgaris, S. typhi, Candida guilliermondii and A. niger are discussed.

Share this       
eutics.com | 523: Origin is unreachable

Error 523 Ray ID: 4e943e041ce1ab64 • 2019-06-19 08:48:08 UTC

Origin is unreachable








What happened?

The origin web server is not reachable.

What can I do?

If you're a visitor of this website:

Please try again in a few minutes.

If you're the owner of this website:

Check your DNS Settings. A 523 error means that Cloudflare could not reach your host web server. The most common cause is that your DNS settings are incorrect. Please contact your hosting provider to confirm your origin IP and then make sure the correct IP is listed for your A record in your Cloudflare DNS Settings page. Additional troubleshooting information here.