All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.


An Efficient Synthesis of (5-(3-Hydroxyquinoxalin-2-Yl)-1, 3, 4-Thiadiazol-2-Yl) Benzamides and (3-(3-Hydroxyquinoxalin-2-Yl)-5-Mercapto-4h-1, 2, 4-Triazol-4-Yl) (Aryl) Methanones

Author(s): Hemalatha Kotakommula, Haripriya Vadapalli, Laxminarayana Eppakayala and Thirumala Chary Maringanti

Ethyl-3-hydroxyquinoxaline-2-carboxylate is reacted with hydrazine hydrate to offered 3- hydroxyquinoxaline-2-carbohydrazide (1), which on condensation with different isothiocyanates gave (2- (3-hydroxyquinoxaline-2-carbonyl) hydrazine-1-carbonothioyl)benzamides (2). Compound 2 is treated with conc. H2SO4 and NaOH to offered (5-(3-hydroxyquinoxalin-2-yl)-1,3,4-thiadiazol-2-yl)benzamides (3) and (3-(3-hydroxyquinoxalin-2-yl)-5-mercapto-4H-1,2,4-triazol-4-yl)(aryl)methanones (4), respectively. The structures of all synthesized compounds were confirmed by spectral analyses.

Share this       

Recommended Conferences