Abstract

A modernised fast tool for computational structure prediction

Author(s): Subin Mary Zachariah*

Drug development and drug discovery are time-consuming and involve many procedures, but several methods introduced modifies the previous making it more easy and simplified. Also, these methods produce more accuracy, and models are made in a short time and take less expenditure in terms of both processing and verifying. For this, appropriate protein structures are selected and their interactions are studied, and based on it new models are made. This involves structural similarity which is one of the key features and their binding on to specific target sites which should also be considered. Based on this criteria model or mannequins are made and their action on specific sites is studied. Methods such as X-ray crystallography and NMR are often used these are not accurate and models formed more complex and difficult to study.