A Comparative Study on Conventional and Microwave Assisted Synthesis of 1,3-Diphenyl-2-propene-1-ones and their Biological Activites

Author(s): Mohammed Rayees Ahmad, V. Girija Sastry, Nasreen Bano, Syed Anwar and K. Mahesh Kumar

Chalcones are synthesized by conventional and microwave assisted synthesis methods. By microwave assisted synthesis, a considerable increase in the reaction rate has been observed and that too, with better yields. We have reported the synthesis and antifungal activity study on substituent effects of 5 chalcones. A lot of genetically defined strains belonging to different yeast genera and species, namely Aspergillus niger and Candida albicans, were used as test organisms. Inhibition of chitin biosynthesis was responsible for fungistatic activity, while the fungicidal effect was a consequence of disturbance of β (1→3) glucan synthase function. The chalcone derivatives may be a useful lead compound for the development of novel antifungal agents.

Share this       
izmir escort izmir escort bursa escort antalya escort izmir escort porno porno izle türk porno eskişehir escort bartın escort burdur escort izmir escort bursa escort porno indir izle istanbul escort istanbul escort bayan escort izmir