44 7460 854 031

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.

Abstract

Formulation and Characterization of Asymmetric Membrane Capsules of Cellulose Acetate

Author(s): S. Bharath and R. H. Shobha Rani

Asymmetric membranes are commonly used in a variety of membrane separation processes such as reverse osmosis, ultrafiltration and dialysis. It consists of a relatively thin, denser outer membrane supported on a thick porous substrate. The use of asymmetric membranes as rate controlling systems are fairly new and novel. The asymmetric membrane capsule dosage form is a controlled drug delivery device that consists of a drug surrounded by a membrane, which has an asymmetric structure. The present investigation aimed for the development and evaluation of asymmetric membrane capsules of cellulose acetate, which could be used for the controlled drug delivery systems, independent of the drug core formulation and offer a major practical advantage in osmotic drug delivery systems. Asymmetric membrane capsules of cellulose acetate was prepared by wet and dry process method of phase inversion technique using a designed pilot model manual capsule shell manufacturing equipment. Characterization of the asymmetric membrane capsule shells for their physical appearance, solubility, crushing strength and surface morphology by scanning electron microscopy and UV spectroscopy were studied. The process employed for the manufacture of capsule shells was novel, industrially feasible and cost effective.


Share this       
Google Scholar citation report
Citations : 9398

International Journal of Chemical Sciences received 9398 citations as per Google Scholar report

Indexed In

  • Google Scholar
  • Open J Gate
  • China National Knowledge Infrastructure (CNKI)
  • Cosmos IF
  • Geneva Foundation for Medical Education and Research
  • ICMJE

View More