Different extracts were prepared from leaves of Teucrium ramosissimum and have been the subject of a preliminary chemical study. This study allowed the identification of these extracts in various secondary metabolites, flavonoids, coumarins, tannins and steroids. The essential oil prepared from the leaves of T. ramosissimum was analyzed by GC and GC/MS. This analysis revealed the presence of monoterpene hydrocarbons, oxygenated monoterpenes and sesquiterpenes. All tested extracts exhibited high biological activities. In addition, our results underline the potential of T. ramosissimum to avoid mutation, genotoxicity and also its antioxidant, Anti-inflammatory, antiulcerogenic and antiproliferative effect.