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Encephalopathy is a general term describing a disease that affects the function or structure of your brain. There are many types of encephalopathy and brain disease. Some types are permanent and some are temporary. Some types are present from birth and never change, while others are acquired after birth and may get progressively worse. This type of encephalopathy occurs when there are multiple traumas or injuries to the brain. These blows to the head lead to nerve damage in the brain. It’s usually found in boxers, football players, or members of the military who have been injured in explosions. Glycine encephalopathy is a genetic, or inherited, condition in which there are abnormally high levels of glycine (an amino acid) in the brain. Symptoms of glycine encephalopathy usually appear in infants soon after birth.