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 Cytogenetics is a part of pathology and hereditary qualities worried about the investigation of ordinary chromosomes and chromosome variations. Old style cytogenetics permits minute perception of entire chromosomes so as to evaluate their number and structure. Atomic cytogenetics utilizes particular procedures, for example, fluorescence in situ hybridization (FISH) and exhibit similar genomic hybridization (aCGH) to assess submicroscopic chromosomal areas. Both old style and sub-atomic cytogenetic methods are utilized to examine established and obtained chromosome variations from the norm. Most as of late, cutting edge sequencing has been added to the cytogenetic lab armory, to permit definite distinguishing proof of breakpoints in chromosome improvements. Every one of these methods will be talked about in more detail in ensuing segments.