BioChemistry: An Indian Journal
ISSN (PRINT): 0974-7427

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Comparitive Genome Hybridization Scholarly Peer-review Journal

Relative genomic hybridisation (CGH) is a strategy that allows the identification of chromosomal duplicate number changes without the requirement for cell refined. It gives a worldwide outline of chromosomal increases and misfortunes all through the entire genome of a tumor. Tumor DNA is named with a green fluorochrome, which is along these lines blended (1:1) with red named ordinary DNA and hybridized to typical human metaphase arrangements. The green and red marked DNA pieces go after hybridisation to their locus of cause on the chromosomes. The green to red fluorescence proportion estimated along the chromosomal hub speaks to misfortune or addition of hereditary material in the tumor at that particular locus. Notwithstanding a fluorescence magnifying instrument, the method requires a PC with committed picture investigation programming to play out the examination. This survey intends to give a nitty gritty conversation of the CGH strategy, and to give a convention an accentuation on critical advances.

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Relevant Topics in Biochemistry

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Citations : 281

BioChemistry: An Indian Journal received 281 citations as per Google Scholar report

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