Scientific Reviews and Chemical Communications
ISSN: 2277-2669

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Blastomycosis

 Blastomycosis is a fungal infection caused by inhaling Blastomyces dermatitidis spores. If it involves only the lungs, it is called pulmonary blastomycosis In those with weak immune systems, the disease can spread to other areas of the body, including the skin and bones. Blastomyces dermatitis is found in the soil and decaying organic matter like wood or leaves. Participating in outdoor activities like hunting or camping in wooded areas increases the risk of developing blastomycosis. There is no vaccine, but the disease can be prevented by not disturbing the soil.[7] Treatment is with itraconazole for mild or moderate disease and amphotericin B for severe disease. With both, the duration of treatment is 6–12 months.[8] Overall, 4-6% of people who develop blastomycosis die; however, if the central nervous system is involved, this rises to 18%. People with AIDS or on medications that suppress the immune system have the highest risk of death at 25-40%.

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