Research & Reviews in BioSciences
ISSN 0974-7532

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Antibiotic Production

Antibiotic is one among the foremost important commercially exploited secondary metabolites produced by bacteria, fungi and Streptomyces and employed during a wide selection . Most of the antibiotics used today are from the microbes. Bacteria are easy to isolate, culture, maintain and to enhance their strain. Bacillus species being the predominant soil bacteria due to their resistant endospore formation and production of important antibiotic like polymyxin, bacitracin etc. are always found inhibiting the expansion of the opposite organisms. within the present research study, screening of bacteria, fungi and Streptomyces with potential antibiotic activity was administered . Among the microbes isolated and identified, Bacillus subtilis , Penicillium chrysogenum and Streptomyces spwere selected on the idea of their anti-bacterial activity. The inhibitory activities of the isolated microorganisms were checked against Staphylococcus aureus (ATCC 29213), Pseudomonas aeruginosa (ATCC 27853), Escherichia coli (ATCC 25922) and Klebsiella pneumonia (ATCC 4352). it had been observed that Penicillium chrysogenum metabolites showed maximum antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli and Klebsiella pneumonia with a zone of inhibition of 17mm, 11mm, 19.8mm and 8.2mm respectively. Bacillus subtilis metabolites showed activity against Staphylococcus aureus and Pseudomonas aeruginosa measured as zone of inhibition of 13.4mm and 13.8mm respectively whereas Streptomyces sp showed minimum activity against all the four tested organisms.

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Citations : 627

Research & Reviews in BioSciences received 627 citations as per Google Scholar report

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