Abstract

Reduction of acetophenone derivatives by Spirulina platensis and Nostoc minutum

Author(s): Takamitsu Utsukihara, Masahiro Koshimura, Chika Abe, Takuya Matsumiya, C.Akira Horiuchi

The reduction of acetophenone derivatives using Spirulina platensis and Nostoc minutum was investigated. It was found that acetophenone derivatives 1a-1o were reduced with good enantioselectivity. The reduction followed PrelogÂ’s rule, giving the (S)-alcohols in all cases.