Bone marrow edema is a condition when excess fluids within the bone marrow build up and cause swelling. It's often caused by a response to an injury, like a broken bone or a bruise, or a more chronic condition like osteoporosis. Bone marrow edema most ordinarily occurs within the hips, knees and ankles during this case, bone marrow edema of the knee may be a main explanation for localized knee and joint pain, and is merely diagnosable via a Magnetic Resonance Imagining test (MRI). Top Open access (OA) may be a set of principles and a variety of practices through which research outputs are distributed online, freed from cost or other access barriers.With open access strictly defined (according to the 2001 definition), or libre open access, barriers to copying or reuse also are reduced or removed by applying an open license for copyright. The most focus of the open access movement is "peer reviewed research literature." Historically, this has centered mainly on print-based academic journals. Whereas conventional (non-open access) journals cover publishing costs through access tolls like subscriptions, site licenses or pay-per-view charges, open-access journals are characterised by funding models which don't require the reader to pay to read the journal's contents. Open access are often applied to all or any sorts of published research output, including peer-reviewed and non-peer reviewed academic journal articles, conference papers, theses, book chapters, and monographs.