Synthesis of new structures of imidazolium salts on the rout to possible drugs

Author(s): Eyad Mazin Mallah

 As result of the strongly basic character of heterocyclic carbenes 1, they react with Broenstedt acids and have consequently been used as selective deprotonation reagents. The 2H-imidazolium salts formed by this method are accessible by other routes, alkylation of 2H-imidazoles, cyclization reactions or from the thiones and nitric acid, and may be used as precursors in the synthesis of 1 through deprotonation.

Share this       
Get the App