Salmonella osteomyelitis is not unusual amongst children with sickle cell sickness. Most normally, it occurs in the long bones of extremities and causes considerable morbidity in this populace. Salmonella osteomyelitis in wholesome youngsters is rare. Though in the growing countries, S. Typhi and non-typhoidal Salmonella infections are common; osteomyelitis related to those organisms in healthful youngsters is uncommon. Small bones are hardly ever suffering from Salmonella species. We gift a healthy toddler with osteomyelitis of his tarsal bones, caused by non-typhoidal Salmonella species. Chronic relapsing osteomyelitis with Salmonella spp has been described inside the literature, however there is constrained statistics in youngsters. Moreover, there is no consensus regarding the fine treatment modalities to save you persistent Salmonella osteomyelitis. However, higher failure charges were related to patients handled with antibiotics, while in comparison to a aggregate of antibiotics and surgical procedure.