Neisseria gonorrhoeae, additionally known as gonococcus (singular), or gonococci (plural) is a species of Gram-terrible diplococci micro organism isolated via Albert Neisser in 1879. It reasons the sexually transmitted genitourinary infection gonorrhea in addition to other varieties of gonococcal disease along with disseminated gonococcemia, septic arthritis, and gonococcal ophthalmia neonatorum. It is oxidase fine and cardio, and it survives within neutrophils. Culturing it requires carbon dioxide supplementation and enriched agar (chocolate agar) with numerous antimicrobials. It exhibits antigenic variant via recombination of its pili and surface proteins that interact with the immune device. Sexual transmission is possible through vaginal, anal, or oral sex. Sexual transmission may be avoided through using barrier protection. Perinatal transmission might also occur in the course of childbirth and can be avoided by antibiotic treatment of the mother earlier than beginning and the application of antibiotic eye gel at the eyes of the new child. After an episode of gonococcal infection, infected persons do now not expand immunity to destiny infections. Reinfection is viable because of N. Gonorrhoeae's potential to keep away from the immune machine through varying its surface proteins.