Lc Ms Applications

 The LC-MS method is beneficial for the detection of steroid tablets in frame fluids and in profiling endogenous steroids. Steroid sulfates were detected with high sensitivity the usage of this approach. Plasmaspray has been used to test saliva for steroid hormones in sufferers tormented by congenital adrenal hyperplasia.Amino acids had been one of the first compounds analyzed using LC-MS coupled with laser desorption and thermospray. Nucleosides, nucleotides, saccharides, peptides, and proteins have been all analyzed and their molecular weights were decided the use of LC-MS coupled with electrospray. Bile acids have additionally been decided using LC-MS and thermospray.Ultra-pure additives and solvents together with acetic acid, acetonitrile, ammonium acetate, ammonium bicarbonate, ammonium fluoride, and ammonium hydroxide are to be had from Sigma Aldrich to be used in LC-MS systems.

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