Journal of Current Chemical and Pharmaceutical Sciences
ISSN: 2277-2871

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In-Silico Modelling In Drug Development

The use and utility of computational models in drug development has significantly grown in the last decades, fostered by the availability of high throughput datasets and new data analysis strategies. These in silico approaches are demonstrating their ability to generate reliable predictions as well as new knowledge on the mode of action of drugs and the mechanisms underlying their side effects, altogether helping to reduce the costs of drug development. The aim of this review is to provide a panorama of developments in the field in the last two years. In silico tools have been widely used to enhance solubility and permeability. PBPK modelling also supports formulation efforts to optimise in vivo exposure. 

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Citations : 3927

Journal of Current Chemical and Pharmaceutical Sciences received 3927 citations as per Google Scholar report

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