Enzymes are the biocatalysts that are capable of mediating many biological reactions and conversion of element into other intermediate products then on to the ultimate product. Coming to their activity, total enzyme won't be involved in any conversion of substrate to a product. Only, a selected a part of the enzyme named “active site” is involved within the reaction phenomenon. Any modifications at the site will cause the activity change of that specific enzyme and even which may make an enzyme to lose its activity totally and permanently. so as to form an enzyme to point out its maximum potency in conversion of substrate to desired product, many parameters got to be optimized which include pH, temperature, concentration of enzyme, concentration of substrate, response time and even many modifications got to be done at the genetic level of that specific enzyme so as to control the enzyme altogether the possible ways to offer maximum yield of the specified product yield and desired product quality. Until all the parameters required for the higher production of desired product aren't optimized, that process won't be approved to scale-up studies at higher quantities. Optimizing all the parameters favouring the higher production of the merchandise will let the size up studies to pilot scale then to industrial level production are often done successively. The impact factor (IF) or journal impact factor (JIF) of a tutorial journal is a scientometric index that reflects the yearly average number of citations that articles published within the last two years during a given journal received. It’s frequently used as a proxy for the relative importance of a journal within its field; journals with higher impact factors are often deemed to be more important than those with lower ones.