Toxicity is how much a concoction substance or a specific blend of substances can harm an organism. Toxicity can allude with the impact on an entire creature, for example, a creature, bacterium, or plant, just as the impact on a base of the life form, for example, a cell (cytotoxicity) or an organ, for example, the liver (hepatotoxicity). By expansion, the word might be figuratively used to depict poisonous impacts on bigger and progressively complex gatherings, for example, the nuclear family or society on the loose. Some of the time the word is pretty much interchangeable with harming in regular utilization. A focal idea of toxicology is that the impacts of a toxicant are portion subordinate; even water can prompt water inebriation when taken in too high a portion, though for even an extremely poisonous substance, for example, snake venom there is a portion underneath which there is no discernible harmful impact. Considering the restrictions of this portion reaction idea, a novel Drug Toxicity Index (DTI) has been proposed recently. DTI rethinks sedate harmfulness, distinguishes hepatotoxic medications, gives unthinking bits of knowledge, predicts clinical results and has potential as a screening device. The top open access journals are freely available on the public internet domain, allowing any end users to read, download, copy, distribute, prink, search or link to the full texts of the articles. These provide high quality, meticulously reviewed and rapid publication, to cater the insistent need of scientific community. These journals are indexed with all their citations noted. The top open access journals are indexed in SCOPUS, COPERNICUS, CAS, EBSCO and ISI.