Synthesis, Characterisation and Antibacterial Activity of some New 2,5-Dimethoxy-3,6-Bis (Arylamino) Cyclohexa-2,5-Diene 1-4-Dions

Author(s): Ch. Sudhakar, M. Komal Reddy and K. Raghava Raju

A series of some new substituted 2,5-dimethoxy-3,6-bis(arylamino)cyclohexa-2,5-diene-1,4-diones has been synthesized by the condensation of 2,5-dibromo-3,6-dimethoxy-1,4-benzoquinone with substituted aromatic primary amines in the presence of anhydrous sodium acetate in ethanol. The structures of newly synthesized compounds were characterized by using IR, 1H NMR, Mass spectral and elemental analysis data. In addition, the antibacterial activity of these compounds has been evaluated against Gram positive and Gram negative bacteria using Streptomycin as standard drug.

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