Abstract
Microbial Chemistry Perspectives in Toxicological Studies of Chemical and Pharmaceutical Compounds
Author(s): Ricardo J. Alvarez-MendozaToxicological studies are essential for evaluating the safety of chemical and pharmaceutical compounds prior to clinical or environmental exposure. Microbial chemistry contributes significantly to toxicological assessment by providing insights into chemical transformation, bioactivation, and detoxification processes mediated by microorganisms. Microbial metabolism can alter the toxicity profile of chemical substances, influencing their biological impact. This article examines the role of microbial chemistry in toxicological studies, emphasizing microbial biotransformation, toxicity prediction, and safety evaluation of microbial-derived and chemically synthesized compounds.Toxicological studies are essential for evaluating the safety of chemical and pharmaceutical compounds prior to clinical or environmental exposure. Microbial chemistry contributes significantly to toxicological assessment by providing insights into chemical transformation, bioactivation, and detoxification processes mediated by microorganisms. Microbial metabolism can alter the toxicity profile of chemical substances, influencing their biological impact. This article examines the role of microbial chemistry in toxicological studies, emphasizing microbial biotransformation, toxicity prediction, and safety evaluation of microbial-derived and chemically synthesized compounds.
