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Abstract

Microbial Chemistry as a Driving Force in Contemporary Pharmaceutical Chemistry

Author(s): Kunal R. Bhattacharya

Pharmaceutical chemistry has evolved significantly with the incorporation of microbial chemistry as a central research and production strategy. Microorganisms possess sophisticated enzymatic systems capable of synthesizing structurally complex and biologically active molecules that are difficult to obtain through conventional chemical synthesis. These microbial products form the backbone of numerous therapeutic agents, including antibiotics, antifungals, anticancer drugs, and immunomodulators. Advances in microbial fermentation, metabolic engineering, and analytical techniques have strengthened the integration of microbial chemistry into pharmaceutical chemistry. This article presents an in-depth examination of the chemical principles governing microbial contributions to pharmaceutical chemistry, highlighting their importance in drug discovery, development, and sustainable manufacturing.


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