GC-MS Determination of the Bioactive Components of Microcosmus Exasperatus Heller, 1878

Author(s): V. K. Meenakshi, S. Gomathy, S. Senthamarai, M. Paripooranaselvi and K. P. Chamundeswari

Bioactive components of the methanolic extract of simple ascidian Microcosmus exasperatus was investigated using Perkin Elmer Gas chromatography-Mass Spectrometry. The mass spectra of the components were matched with the data available in the National Institute of Standards and Technology (NIST) library. The analysis revealed the presence of nine chemical constituents of which the major are (Z)-9-Octadecenamide (47.31%), 3, 5-bis-trimethylsilyl-2, 4, 6- cycloheptatrien-1-one, (15.50%), Trimethylsilyl ether 1-monolinoleoyl glycerol (10.54%). Of the nine components identified, seven components are being reported for the first time from ascidians. 2-Isopropyl-5-methyl-1-heptanol (RT : 5.33), Isotridecanol (RT : 5.43), 2-methyl-2-undecanethiol (RT : 5.57), 9,9-dimethoxybicyclo[3.3.1]nona-2, 4-dione (RT : 13.13), Mono (2-ethylhexyl) ester-1,2-benzenedicarboxylic acid (RT : 20.91), (Z)-9-Octadecenamide (RT : 24.46), Trimethylsilyl ether 1-monolinoleoylglycerol (RT : 28.34) showed antimicrobial, anti-inflammatory, antioxidant and antifouling activities

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