Alzheimer's disease and Sleep in people with depression have been described extensively in both clinical and epidemiological studies. People struggling with depression are likely to have difficulty falling asleep or staying asleep. Alzheimer's disease and Sleep are linked in an interesting way. Sleep Aids and Insomnia symptoms can affect your sleep, and symptoms of sleep disorders like insomnia may also lead to depression. Good sleep hygiene is the antidote to sleep deprivation. People accumulate sleep debt when they lose a specified amount of sleep each night, and the only way to repay that debt is to get more sleep.